…is a bad idea when you’ve been going in mini-gonzo mode for several days (8 hours sleep over 88 hours) you will wake up with your computer in suspended mode and the post you’ve just finished sitting unposted because you fell asleep before you could add set up categories and post.
this is particularly true if your bed is VERY comfortable.
Da Techguy's (no longer backup) Blog 
Just a hint – keep your eyes on those locks.